Research & Development

Research Projects

Introduction

NDTL has state of the art facilities for research and is engaged in conducting research on various projects. The research papers are presented in the International and National conferences and published in indexed journals. The first ever Ph.D. thesis “Detectability of Indian glucocorticosteroid preparations in sports persons: Effect on the endogenous steroid profile” was submitted in April 2009 by Madhusudan Reddy and the degree has been awarded.

Projects Accomplished
1. Detectability of Corticosteroid in various Indian preparations: Effect on Endogenous steroid profile
2. Characteristics of IEF Patterns and SDS-PAGE Result of Indian EPO Biosimilars.
3. Establishing Reference Range for endogenous Steroids in Indian Sportspersons and to study the effect of ethnicity and steroid abuse on delta values of endogenous steroids.
4. Analytical strategies in the development and utilization of mass spectrometric method for analysis of Stimulant & Narcotics.
5. Effect of Ethnicity and Anabolic Steroid Abuse on Delta Value of Endogenous Steroids
6. Rapid Screening in Doping Analysis: Seperation and Detection of Doping Agents be Liquid and Gas Chromatographic Mass Spectrometric Analysis

NDTL is actively engaged in various research projects on doping analysis in the field of human & horse dope testing. Following are the ongoing Ph.D / Research projects in NDTL:

Current Projects
1. Detection of Synthetic glucocortico steriods, stimulants and anabolic steriods in Indian herbal drugs and supplements Funded by National Anti Doping Agency (NADA)
2. Discrimination of biological and synthetic origin of anabolic steroids in human urine: Correlation between GCMSD & Isotope Ratio Mass Spectrometry. Ministry of Youth Affairs and Sports , Govt. of India
3. An Analytical approach for the Screening of Performance Enhancing Substances from various Dietary Supplements & to study their excretion profile using Chromatographic-Mass Spectrometric Technique. —do—
4. Development of analytical tools for the Detection and Identification of performance enhancing Peptides in Biological Specimen

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5. An analytical approach for the Detection of Corticosteroids in Human and Horse Biological Specimen using Chromatographic and Mass Spectrometric Technique

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6. To study the effect of various preparation of Testosterone on Steroid Profiling and Delta Value of 13C/12C of Testosterone Metabolite in volunteers with Normal/Abnormal Testosterone/ Epitestosterone (T/E) Ratio

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7. Indian Herbal Drugs : Identification of stimulant, narcotics and other substances with potential of ergogenic aids in sports

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8. 8. Characterization of physiochemical properties and analysis of liposomes in human biological samples using hyphenated analytical technique

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9. Detection of Stanozolol conjugated metabolites by liquid chromatography tandem-mass spectrometry

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10. Prednisone excretion study and identification of its marker metabolites.

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11. Rapid determination of urinary phthalates using liquid chromatography tandem mass spectrometry

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12. Identification of various banned small peptides in human urine using liquid chromatography tandem mass spectrometry

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